Sample pooling methods for efficient pathogen screening: Practical implications

Efficient pooling designs for library screening.

We describe efficient methods for screening clone libraries, based on pooling schemes that we call "random k-sets designs." In these designs, the pools in which any clone occurs are equally likely to be any possible selection of k from the v pools. The values of k and v can be chosen to optimize desirable properties. Random k-sets designs have substantial advantages over alternative pooling sch...

The ethical implications of screening for HIV: whose choice reigns?

islanding detection methods for microgrids

امروزه استفاده از منابع انرژی پراکنده کاربرد وسیعی یافته است . اگر چه این منابع بسیاری از مشکلات شبکه را حل می کنند اما زیاد شدن آنها مسائل فراوانی برای سیستم قدرت به همراه دارد . استفاده از میکروشبکه راه حلی است که علاوه بر استفاده از مزایای منابع انرژی پراکنده برخی از مشکلات ایجاد شده توسط آنها را نیز منتفی می کند . همچنین میکروشبکه ها کیفیت برق و قابلیت اطمینان تامین انرژی مشترکان را افزایش ...

Practical approaches to efficient screening: information-rich screening protocol.

The past approach of high-throughput screening of everything in the corporate collection has been shown to be very expensive in terms of reagents cost, disposal cost, and compound collection depletion. It is well known that screening campaigns produce several hits, of which only 50% confirm on average. More efficient ways of screening can provide an informative structure-activity relationship (...

CpG-PCR combined with sample pooling and mutant enrichment for CpG mutation screening in population studies.

1. Ablin RJ, Soanes WA, Bronson P, Witesby E. Precipitating antigens of the normal human prostate. J Reprod Fertil 1970;22:573–5. 2. Peehl DM. Prostate specific antigen role and function [Review]. Cancer 1995;75:2021–6. 3. Diamandis EP. New diagnostic applications and physiological functions of prostate-specific antigen [Review]. Scand J Clin Lab Invest 1995;55:105–12. 4. Graves HCB. Nonprostat...